Systems Biology Concentration

For Majors who wish to focus on systems, integrative aspects, information, regulation or control processes in life sciences, including molecular and cellular biosystems. 

Systems biology integrates knowledge of genetic and molecular function to understanding how a whole cell works as a system and from there to multi-cellular systems such as organs and whole animals. Cybernetics principles serve to integrate these living system components into a structured whole, via mathematical and system theoretic models and simulations capable of predicting biosystem function and behavior.

Required coursework consists of a common CORE of 3 basic courses (16 or 18 units), plus a coherent selection of coursework consisting of 12 or more additional units in one of 2 subareas or a coherent combination of these subareas.  Courses must be selected in consultation with the faculty mentor and approved by the program chair.

APPROVED LIST - CONCENTRATIONS FOR THE ACADEMIC YEAR 2007-2008 (updated 1/16/08)

Recommended courses are shown with *.

Consult Curricular & Courses at www.registrar.ucla.edu/catalog/ for detailed course descriptions.

See Schedule of Classes for this year's course offerings.


REQUIRED CORE - Courses in Molecular and Cellular Biology and Physiology

1. MCDB 144 Molecular Biology (Fall) 5 units
2. MCDB 100 Introduction to Cell Biology (Winter) 5 units
3. One of the following :
Phys Sci 166 Animal Physiology (Summer only) 6 units
  OR
EE Biol 170 Animal Environmental Physiology (Fall) 6 units
  OR
Biomed CM102 and CM103
Basic Human Biology for Biomedical Engineers I & II
(Fall, Winter sequence)
4 + 4 = 8 units


SUBAREA 1:
Information and Control in Biosystems

Bioeng 180 System Integration in Biology, Engineering and Medicine I 4 units
Bioeng 180L System Integration in Biology, Engineering and Medicine I Laboratory 3 units
Bioeng 181 System Integration in Biology, Engineering and Medicine II 4 units
Bioeng 181L System Integration in Biology, Engineering and Medicine II Laboratory 3 units
Biomath 108  Introduction to Modeling in Neurobiology 4 units
Biomath C108C Introduction to Neural Networks: Modeling and Applications 4 units
Biomath 206 Introduction to Mathematical Oncology 4 units
CS M296D Computational Cardiology 4 units
Neurosci M148 Neuronal Signaling in Brain 4 units
Neurosci 205 Systems Neuroscience 4 units
Physiol Sci 107 Systems Anatomy 5 units
Physiol Sci C144 Neural Control of Physiological Systems 5 units
Physiol Sci M145 Neural Mechanisms Controlling Movement 5 units
Physiol Sci M173 Anatomy and Physiology of Sense Organs 4 units


SUBAREA 2:
Molecular and Cellular Biosystems

Biomath 106 Introduction to Cellular Modeling 4 units
Bioeng 110 Biotransport and Bioreaction Processes 4 units
Biomed Eng C101/C201 Introduction to Biomedical Engineering 4 units
Chem 153A/153AH Biochemistry: Introduction to Structure, Enzymes and Metabolism
4 units
MCDB C139/CM220 Cell, Developmental and Molecular Neurobiology 6 units
MCDB M140 Cell Biology: Cell Cycle 5 units
MCDB CM156/CM256 Human Genetics 4 units
MCDB CM160/CM252 Biological Catalysis 4 units
MCDB 165A Biology of Cells 5 units
MCDB 165B Molecular Biology of Cell Nucleus 5 units
MCDB  CM169/CM223A Cell Biology 4 units
Psych 119A Neuropsychopharmacology 4 units
Psych 119D Behavioral Neuropharmacology 4 units


METHODOLOGY PERTINENT TO BOTH SUBAREAS -
These courses can be included in either S1 or S2, to make up additional units for the total 28 units required in the concentration.

Biomath 220 Kinetic and Steady State Models in Pharmacology and Physiology 4 units
Biomath M230 Computed Tomography: Theory and Applications 4 units
Biomath M271 Statistical Methods in Computational Biology 4 units
Chem 110A Physical Chemistry: Chemical Thermodynamics 4 units
Chem 156 Physical Biochemistry 4 units
Chem C160A/CM260A Introduction to Bioinformatics (4 units; NEW Pre-Requisite: PIC 60 or CS 180) 4 units
Chem C160B/C260B Algorithms in Bioinformatics and Systems Biology 4 units
Chem Eng CM145 Molecular Biotechnology for Engineers 4 units
CS CM186C/CM286C Biomodeling Research and Research Communication 2 to 4 units
CS M296B Optimal Parameter Estimation and Experiment Design for Biomedical Systems 4 units
EE 131B Introduction to Stochastic Processes 4 units
EE 136 Introduction to Engineering Optimization Techniques 4 units
EE 142 Linear Systems: State-Space Approach 4 units
MAE 105A Introduction to Engineering Thermodynamics 4 units
Math 134 Linear and Nonlinear Systems of Differential Equations 4 units
Math 136 Partial Differential Equations 4 units
Math 151A Applied Numerical Methods 4 units
Math 151B Applied Numerical Methods 4 units
Math 171A Stochastic Processes 4 units
Physics 105A Analytic Mechanics 4 units
Physics 112 Thermodynamics 4 units