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Joseph Distefano III

joe.jpgJOSEPH DiSTEFANO III, Professor of Computer Science & Medicine
4711 Boelter Hall
Los Angeles, CA 90095-1596
tel: (310) 825-7482, fax: (310) 825-2273

Lab and Affiliation websites

Areas of Interest

  • Dynamic systems biology modeling and simulation
  • Human disease models, their dynamics and optimal control (treatment)
  • Physiological, pharmacological and toxicological systems applications

Areas of Interest

Distinguished Professor Joe DiStefano III was born in Brooklyn in 1938, graduated from Stuyvesant High School in 1956, received the BEE in Electrical Engineering from CCNY in 1961, and MS and PhD degrees from UCLA – in Control Systems (MS – 1964), and Computer Methodology, Applied Math, Biocybernetics & Physiology (PhD – 1966).

Joe joined the UCLA Engineering faculty in 1966, Medicine faculty in 1970, Computer Science faculty in 1982 and became chair of the undergrad Cybernetics Interdepartmental Program (IDP) in 1981.  He received 3 prestigious teaching awards at UCLA – the UCLA Distinguished Teaching Award in 2003, the Ebi Award for Creative Teaching in 2003, and the Lockeed-Martin Award for Teaching Excellence in 2004.  He also was a Senior Fulbright-Hays Scholar in Italy in 1979, and is a Fellow of the Biomedical Engineering Society.

He Chairs the undergrad Computational & Systems Biology IDP, the Computational Systems Biology grad program in Computer Science, Co-Chairs the Biosystem Science and Engineering Major in the Biomedical Engineering graduate IDP and directs the UCLA Biocybernetics Research Laboratory.  His research is math modeling oriented – systems biology, dynamic systems modeling, simulation and optimization – and has always been integrated with “wet-lab” data, mostly in rats and fish from his own lab.  Currently, it is “translational” – with a focus on human health and disease processes (cancer, thyroid, diabetes, etc) and optimal therapies, along with their pharmacological and toxicological influences.

He has authored or coauthored two editions of Feedback and Control Systems (Schaum-McGraw-Hill 1967 and 1991), more than 200 research articles, and is nearly finished with his opus textbook: Dynamic Systems Biology Modeling and Simulation (2011?).